Search the Studies

106 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
001746-DKPilot Study of Isocaloric Time Restricted Eating on Ketone Metabolism and ImmunoregulationRecruitment has not started18-50 YearsNIDDK
001707-DKVariability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric DoseRecruitment has not started18-99 YearsNIDDK
001690-DKEffect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic RateParticipants currently recruited/enrolled18-65 YearsNIDDK
001680-DKDiet Order Effects of Low Fat vs. Low Carb Diets on Body Fat ChangeRecruitment has not started18-50 YearsNIDDK
001651-DKA Pilot Study to Assess Feasibility of Adipose Tissue Triglyceride (TG) Labelling in Familial Partial Lipodystrophy (FPLD)Participants currently recruited/enrolled18-65 YearsNIDDK
001606-DKA Pilot Study of the Combination of VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis BRecruitment has not started18-65 YearsNIDDK
001515-DKOpen Label Phase 2 Clinical Study of Peginterferon Lambda and Lonafarnib Boosted with Ritonavir 48-Week Combination Therapy for Delta HepatitisRecruitment has not started18-120 YearsNIDDK
001125-DKOptimizing HBV Care Cascade among Foreign-Born in the United States (FOCUS-HBV Study)Participants currently recruited/enrolled18-100 YearsNIDDK
001058-DKA Phase 1b/2a Open-label Multiple-ascending Dose Exploratory Study of CRN04894 in ACTH-dependent Cushing's Syndrome (Cushing's Disease or Ectopic ACTH Syndrome)Participants currently recruited/enrolled18-75 YearsNIDDK
000911-DKDinner Time for Obesity and Prediabetes (DTOP)Participants currently recruited/enrolled18-50 YearsNIDDK
000908-DKPeripheral Blood and Urine Immune Cell Phenotyping in Membranous Nephropathy using FACS and Single Cell RNA-seqParticipants currently recruited/enrolled18-125 YearsNIDDK
000869-DKThe Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy ExpenditureParticipants currently recruited/enrolled18-60 YearsNIDDK
000757-DKNatural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects with LipodystrophyParticipants currently recruited/enrolled0-98 YearsNIDDK
000756-DKPhase II Study of Growth Hormone Inhibition Using Pegvisomant In Severe Insulin ResistanceParticipants currently recruited/enrolled18-65 YearsNIDDK
000748-DKAnalysis of the Utility of Polygenic Scores for Prediction of Incident Type 2 Diabetes Across Multiple Ancestry GroupsCompleted Study; data analyses ongoing18-99 YearsNIDDK
000665-DKA Randomized Double-Blind Placebo-Controlled Study of the LEPR Agonist Antibody REGN4461 for the Treatment of Metabolic Abnormalities in Patients with Familial Partial LipodystrophyCompleted Study; data analyses ongoing18-90 YearsNIDDK
000617-DKA Natural History Study of Metabolic Sizing in Health and DiseaseParticipants currently recruited/enrolled2-99 YearsNIDDK
000545-DKPrevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell Transplant: A Prospective Natural History StudyRecruitment has not started3-125 YearsNIDDK
000494-DKNatural History of Fontan Associated Liver Disease and the Evaluation of Biomarkers for Disease Severity AssessmentParticipants currently recruited/enrolled18-100 YearsNIDDK
000393-DKDiabetic Kidney Disease and Related Complications in American Indians with Type 2 DiabetesClinical hold/Recruitment or enrollment suspended18-99 YearsNIDDK
000344-DKNatural History Study of Parathyroid DisordersParticipants currently recruited/enrolled0-100 YearsNIDDK
000247-DKEvaluation of Patients with Gastrointestinal DiseaseParticipants currently recruited/enrolled18-120 YearsNIDDK
000220-DKPhase II Trial of the Combination of Alpha-lipoic Acid and Mirabegron in Women and in Men with ObesityRecruitment has not started18-65 YearsNIDDK
000172-DKThe Impact of the Food Environment and Psychosocial Stress from the COVID-19 Pandemic on Eating Behavior and Weight ChangeNo longer recruiting/follow-up only18-99 YearsNIDDK
000130-DKUnraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research ApproachParticipants currently recruited/enrolled18-90 YearsNIDDK
000118-DKProspective Cohort Study to Determine the Response to COVID-19 Vaccination and Prevalence of COVID-19 in Subjects with Chronic Liver DiseaseNo longer recruiting/follow-up only18-100 YearsNIDDK
000079-DKThe Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid CancerParticipants currently recruited/enrolled18-98 YearsNIDDK
000043-DKDeveloping Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar IntakeParticipants currently recruited/enrolled18-65 YearsNIDDK
22-DK-0002Effect of Ultra-processed versus Unprocessed Diets on Energy MetabolismParticipants currently recruited/enrolled18-60 YearsNIDDK
20-DK-0168LYNC-LD Prospective Multicenter Natural History Study of Lipodystrophy Syndromes to Determine Prevalence, Incidence and Predictors of Diabetes and Severe Hypertriglyceridemia, and their Complications.Participants currently recruited/enrolled3-120 YearsNIDDK
20-DK-0079A Randomized, Double-Blinded, Placebo-Controlled Study of REGN4661, A Leptin Receptor Agonist Antibody, In Patients with Generalized LipodystrophyCompleted Study; data analyses ongoing12-90 YearsNIDDK
20-DK-0018Prebiotics and Metformin Influences Gut and Hormones in Type 2 Diabetes YouthCompleted Study; data analyses ongoing10-25 YearsNIDDK
19-DK-0072Non-Alcoholic Fatty Liver Disease, the Hepatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)Participants currently recruited/enrolled18-125 YearsNIDDK
19-DK-0067Effect of Low Fat versus Low Carbohydrate Diets on Energy MetabolismCompleted Study; data analyses ongoing18-50 YearsNIDDK
19-DK-0066The Evaluation and Management of Endocrine-Related Conditions and PhysiologyParticipants currently recruited/enrolled18-90 YearsNIDDK
19-DK-0050The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid CancerParticipants currently recruited/enrolled18-90 YearsNIDDK
18-DK-N071Early Tracking of Childhood Health Determinants StudyParticipants currently recruited/enrolled0-99 YearsNIDDK
18-DK-0132Brain Dopamine Function in Human ObesityCompleted Study; data analyses ongoing18-125 YearsNIDDK
18-DK-0123Treatment of Chronic Delta Hepatitis with Lonafarnib, Ritonavir and Lambda InterferonCompleted Study; data analyses ongoing18-125 YearsNIDDK
18-DK-0091Long-Term Follow-Up Of Subjects With CHC Who Achieved A Sustained Virological Response Following Therapy With Direct Acting Antiviral AgentsParticipants currently recruited/enrolled18-120 YearsNIDDK
18-DK-0044Effect of Ultra Processed versus Unprocessed Diets on Energy IntakeCompleted Study; data analyses ongoing18-50 YearsNIDDK
18-CH-0031Clinical and Molecular Characteristics of Primary Aldosteronism in BlacksClinical hold/Recruitment or enrollment suspended7-70 YearsNIDDK
17-DK-N004Energy Intake Response to Short-Term Alterations of Energy Expenditure in HumansParticipants currently recruited/enrolled18-55 YearsNIDDK
17-DK-0054The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment with Beta3-Adrenergic Receptor AgonistsParticipants currently recruited/enrolled18-40 YearsNIDDK
17-DK-0013Therapeutic Targets in African-American Youth with Type 2 DiabetesCompleted Study; data analyses ongoing12-25 YearsNIDDK
16-DK-0173MEASuRE: Metreleptin Effectiveness and Safety RegistryParticipants currently recruited/enrolled0-98 YearsNIDDK
16-DK-0143Idiosyncratic Liver Injury Associated with Drugs (ILIAD): A Retrospective StudyParticipants currently recruited/enrolled18-100 YearsNIDDK
16-DK-0125Evaluation of Adults with Endocrine-Related ConditionsParticipants currently recruited/enrolled18-100 YearsNIDDK
16-DK-0068The Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and its Role in MetabolismParticipants currently recruited/enrolled18-125 YearsNIDDK
15-DK-0192Quantifying Weight Regain and the Persistence of Metabolic Adaptation Following Extreme Weight LossCompleted Study; data analyses ongoing18-125 YearsNIDDK
15-DK-0174Dynamic Post-Prandial Metabolism in Patients with Non-Alcoholic Fatty Liver DiseaseCompleted Study; data analyses ongoing18-125 YearsNIDDK
15-DK-0170Treatment of Chronic Delta Hepatitis with Lonafarnib and RitonavirCompleted Study; data analyses ongoing18-99 YearsNIDDK
15-DK-0143Investigation of Viral Kinetics, Interferon Stimulated Genes (ISGs) and mirRNA Among Subjects Infected with Different Hepatitis C Virus Genotypes During Therapy with Sofosbuvir and GS-5816Completed Study; data analyses ongoing18-80 YearsNIDDK
15-DK-0108Natural History of Noncirrhotic Portal HypertensionParticipants currently recruited/enrolled12-100 YearsNIDDK
15-DK-0100A Multidisciplinary Approach to Deciphering the Mechanisms Involved In Microbial Translocation Across the Spectrum of HCV Associated Liver FibrosisCompleted Study; data analyses ongoing18-125 YearsNIDDK
15-DK-0082Mechanisms Associated with Favorable Response to Peginterferon-Alpha Add-on Therapy Following Long-term Nucleos(t)ide Analogue Treatment in Patients with Chronic Hepatitis BCompleted Study; data analyses ongoing18-125 YearsNIDDK
15-DK-0079Observational Study of Hepatitis B Virus (HBV) in Patients Coinfected with Human Immunodeficiency Virus (HIV)Completed Study; data analyses ongoing18-125 YearsNIDDK
15-DK-0003Compassionate Use of Metreleptin in Previously-Treated Patients with Generalized LipodystrophyParticipants currently recruited/enrolled0-98 YearsNIDDK
15-DK-0002Compassionate Use of Metreleptin in Previously-Treated Patients with Partial LipodystrophyNo longer recruiting/follow-up only0-98 YearsNIDDK
14-DK-0195Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitor on Bone Metabolism in Healthy VolunteersCompleted Study; data analyses ongoing18-125 YearsNIDDK
14-DK-0060Famine from Feast: Linking Vitamin C, Red Blood Cell Fragility, and DiabetesParticipants currently recruited/enrolled18-65 YearsNIDDK
14-CH-0028Prospective Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Ectopic Cushing SyndromeParticipants currently recruited/enrolled18-80 YearsNIDDK
13-DK-0212Effect of a Eucaloric Ketogenic Diet on Energy Expenditure: A Pilot StudyCompleted Study; data analyses ongoing18-50 YearsNIDDK
13-DK-0200The Mechanism of Human Non-Shivering Thermogenesis and Basal Metabolic RateParticipants currently recruited/enrolled18-35 YearsNIDDK
13-DK-0091Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir DF versus Tenofovir DF Monotherapy in HBeAg-Positive and HBeAg-Negative Chronic Hepatitis BCompleted Study; data analyses ongoing18-125 YearsNIDDK
13-DK-0090Identifying Risk for Diabetes and Heart Disease in Women: A Study of African-American, African and White Federal Employees and ContractorsCompleted Study; data analyses ongoing25-65 YearsNIDDK
12-DK-0097Energy Expenditure Responses to Different TemperaturesParticipants currently recruited/enrolled18-75 YearsNIDDK
12-DK-0071Combination Entecavir and Peginterferon Therapy in HBeAg-Positive Immune-Tolerant Adults with Chronic Hepatitis BCompleted Study; data analyses ongoing18-40 YearsNIDDK
11-DK-0168Magnetic Resonance of Body, Arterial Wall, and Angiography Imaging for Non- Invasive Assessment of Arterial Distensibility, Endothelial Dysfunction and Atherosclerotic Disease Using 1.5T and High Field (3T) MRI: A Technical Development Study of Cardiac aParticipants currently recruited/enrolled18-100 YearsNIDDK
11-DK-0151Withdrawal of Therapy After Long-Term Oral Nucleos(t)ide Analogue Treatment in Patients with Chronic Hepatitis BCompleted Study; data analyses ongoing18-125 YearsNIDDK
11-DK-0108Observational Study of Persons with Hepatitis B Virus Infection in North America (Cohort Study)Completed Study; data analyses ongoing18-100 YearsNIDDK
10-DK-N091Molecular and Clinical Profile of Diabetes Mellitus and its ComplicationsParticipants currently recruited/enrolled18-99 YearsNIDDK
10-DK-0102Clinical and Genetic Studies in Familial Non-Medullary Thyroid CancerParticipants currently recruited/enrolled7-90 YearsNIDDK
09-DK-0223Rituximab Plus Cyclosporine in Idiopathic Membranous NephropathyParticipants currently recruited/enrolled18-125 YearsNIDDK
09-DK-0097Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese WomenCompleted Study; data analyses ongoing18-55 YearsNIDDK
09-DK-0081Selective Reduction of Dietary Carbohydrate Versus Fat: Effects on Metabolism, Endocrine Physiology, Brain Activity and Reward CircuitryCompleted Study; data analyses ongoing18-45 YearsNIDDK
08-DK-N191The Effects of Transcranial Direct Current Stimulation (TDCS) on Food Intake and Weight LossParticipants currently recruited/enrolled18-60 YearsNIDDK
08-DK-N140Predicting Adaptive ThermogenesisCompleted Study; data analyses ongoing18-60 YearsNIDDK
08-DK-0173A Trial of Segmental Stiffening Wires to Improve the Efficiency and Patient Tolerability of ColonoscopyCompleted Study; data analyses ongoing40-80 YearsNIDDK
08-DK-0149High Dose Ribavirin in Combination with Peginterferon for Patients with Chronic Hepatitis C Genotype 1 Infection Who Have Failed to Respond or Relapsed after Standard TherapyCompleted Study; data analyses ongoing18-65 YearsNIDDK
08-DK-0138A New Method for Determining Gastric Acid Output Using a Wireless CapsuleCompleted Study; data analyses ongoing18-125 YearsNIDDK
08-DK-0098Natural History of Familial Carcinoid TumorParticipants currently recruited/enrolled18-125 YearsNIDDK
08-DK-0004High Sensitivity Screening of Compound Libraries to Discover a Drug for the Treatment of Sickle Cell DiseaseParticipants currently recruited/enrolled18-100 YearsNIDDK
07-DK-N215Study of Short-Term Metabolic Adaptation: Prediction of Weight Change and Effects of Macronutrient ManipulationsCompleted Study; data analyses ongoing18-55 YearsNIDDK
07-DK-0115Natural History of Type 2 Diabetes Mellitus in Children and Young AdultsCompleted Study; data analyses ongoing8-25 YearsNIDDK
07-DK-0077Study of the Phenotype of Overweight and Obese AdultsParticipants currently recruited/enrolled18-100 YearsNIDDK
04-DK-0021Urinary Vitamin C Loss in Subjects with and without DiabetesParticipants currently recruited/enrolled18-65 YearsNIDDK
03-DK-0257Phase II Trial of Effect of Metreleptin Therapy in Severe Insulin ResistanceNo longer recruiting/follow-up only5-80 YearsNIDDK
03-DK-0256Inhibition of Intestinal Glucose Absorption by the Bioflavonoid Quercetin in the Obese and in Obese Type 2 DiabeticsCompleted Study; data analyses ongoing18-65 YearsNIDDK
02-DK-N304Diabetes Prevention Program Outcomes Study (DPPOS)Participants currently recruited/enrolled25-99 YearsNIDDK
01-DK-N117Family Investigation of Nephropathy and Diabetes (F.I.N.D.)Participants currently recruited/enrolled18-99 YearsNIDDK
00-DK-0107Search for Novel Methods to Detect Acute Renal FailureParticipants currently recruited/enrolled3-125 YearsNIDDK
OH99-DK-N019The Food Intake Phenotype: Assessing Eating Behavior and Food Preferences as Risk Factors for ObesityParticipants currently recruited/enrolled18-65 YearsNIDDK
OH82-DK-0136Cross-Sectional and Longitudinal Studies of 'Pre-Diabetes'Completed Study; data analyses ongoing18-55 YearsNIDDK
99-DK-0002Diabetes and Heart Disease Risk in BlacksParticipants currently recruited/enrolled18-70 YearsNIDDK
94-DK-0133Genetic Markers for Focal Segmental GlomerulosclerosisCompleted Study; data analyses ongoing1-125 YearsNIDDK
94-DK-0127Pathogenesis of GlomerulosclerosisCompleted Study; data analyses ongoing2-125 YearsNIDDK
92-DK-0156Studies of Immunologically-Mediated Kidney DiseasesParticipants currently recruited/enrolled10-125 YearsNIDDK
92-DK-0033Pharmacokinetics and Biodistribution of Ascorbic Acid in Healthy Human SubjectsCompleted Study; data analyses ongoing18-35 YearsNIDDK
91-DK-0214Evaluation of Patients with Liver DiseaseParticipants currently recruited/enrolled2-125 YearsNIDDK
91-DK-0066Fasting Hypoglycemia: Diagnosis and TreatmentParticipants currently recruited/enrolled18-120 YearsNIDDK
90-DK-0137Evaluation of the Gastrinoma in Patients with Zollinger-Ellison SyndromeCompleted Study; data analyses ongoing18-100 YearsNIDDK
87-DK-0029Diagnosis and Treatment of Patients with Cystic FibrosisParticipants currently recruited/enrolled4-120 YearsNIDDK
77-DK-0096Studies on Thyroid Nodules and Thyroid CancerParticipants currently recruited/enrolled0-98 YearsNIDDK
77-DK-0002Natural History of Thyroid Function DisordersParticipants currently recruited/enrolled0-98 YearsNIDDK
76-DK-0006Natural History of Disorders of Insulin ResistanceParticipants currently recruited/enrolled0-120 YearsNIDDK
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